The heart of what drives IoT is the digitization of products, services, and processes, improving how we manage individual lives, corporate enterprises, and public institutions. IoT brings new complex problems where information comes from many sources, in many forms, can be real time, or historic, and either limited or massive in scale. In applications information is used to make decisions and take courses of action. In the past it was possible to do that in a comprehensive way for only very high value applications or for important national problems that required national means – to afford the expense of infrastructure dedicated to a single purpose. The evolution of computing, storage, and communications technology now makes it routine and commonplace to extend the paradigm to a much broader set of use cases. The ultimate step is to build the “decision loop” – from data to decision – into autonomous systems, with none or little human intervention, using various forms of Artificial Intelligence, Machine Learning, and Heuristics. The Sessions on this topic will cover advances in Artificial Intelligence and the progression to Autonomous Systems and concentrate on examples of successful deployments and plans for future products and services relevant to the Vertical focus of the Summit.